Synthesis of taurine

Preparation of taurine

Preparation of taurine

Preparation of taurine

An equimolar mixture of monoethanolamine and 96% sulfuric acid is heated rapidly over a free flame until, at a temperature of about 250°, charring begins, necessitating the end of the operation. When the reaction mixture begins to turn brown rapidly the degree of dehydration has been reached, the reaction is complete. On cooling, brown liquid solidifies to a hard, white crystalline cake, which is ground in a mortar with 60% ethanol, filtered, washed again with ethanol yielding 71% of taurine.

J. Am. Chem. Soc., 1935, 57 (11), pp 2328–2328


2-aminoethanesulfonic acid



InChI Key


Canonical SMILES


MeSH Synonyms

Taufon, Tauphon, Taurine, Taurine Hydrochloride, Taurine Zinc Salt (2:1), Taurine, Monopotassium Salt

Depositor-Supplied Synonyms

taurine, 2-aminoethanesulfonic acid, 107-35-7, L-Taurine, tauphon, 2-Aminoethylsulfonic acid, 2-Sulfoethylamine, Ethanesulfonic acid, 2-amino-, O-Due, Aminoethanesulfonic acid, aminoethylsulfonic acid, beta-Aminoethylsulfonic acid, taufon, Taurinum [Latin], Taurina [Spanish], 2-aminoethane-1-sulfonic acid, Aminoethylsulfonate, Taurine [INN], b-Aminoethylsulfonate, 1-Aminoethane-2-sulfonic acid, FEMA No. 3813, 2-Aminoethylsulfonate, CCRIS 4721, AI3-18307, beta-Aminoethylsulfonate, NCI-C60606, b-Aminoethylsulfonic acid, NSC32428, UNII-1EQV5MLY3D, 1-Aminoethane-2-sulfonate, 2-aminoethane sulfonic acid, 2-aminoethanesulfonate, C2H7NO3S, .beta.-Aminoethylsulfonic acid, CHEBI:15891, XOAAWQZATWQOTB-UHFFFAOYSA-N, EINECS 203-483-8, NSC 32428, 107-35-7, 2-Aminoethanesulfonic acid, NCGC00015997-06, DSSTox_CID_1304, DSSTox_RID_76069, DSSTox_GSID_21304, 91105-79-2, CAS-107-35-7, SMR000326743, TAU, Taukard, Taurina, Taurinum, tauric acid, Taurine (TN), Taurine (8CI), S2008_Selleck, 2-aminoethyl sulfonate, PubChem18250, Tocris-0209, 2aminoethanesulfonic acid, 2-aminoethansulfonic acid, AC1L1ARZ, Lopac-T-0625, 1EQV5MLY3D, WLN: Z2SWQ, ACMC-2098vs, bmse000120, bmse000805, bmse000863, 2-Aminoetahanesulfonic acid, 2-amino-ethanesulfonic acid, AC1Q54NS, Ambcb5117231, Taurine [USP:INN:BAN], Ambap107-35-7, Lopac0_001134, SCHEMBL23068, KSC178O6B, MLS000859681, MLS001332383, MLS001332384, ARONIS27193, T0625_SIGMA, T4571_SIGMA, T8691_SIGMA, Taurine (JP16/USP/INN), W381306_ALDRICH, Aminoethylsulfonic acid (JAN), CHEMBL239243, GTPL2379, CHEMBL1708029, 86329_FLUKA, 86329_SIGMA, 86330_FLUKA, CTK0H8760, HMDB00251, MolPort-000-006-300, HMS2093L13, HMS2233D19, HMS3263D09, HMS3370J18, Pharmakon1600-01505463, 2-Aminoethanesulfonic acid, Taurine, HY-B0351, ZINC3809490, Tox21_110277, Tox21_202520, Tox21_501134, ANW-15782, BDBM50357220, LS-439, MFCD00008197, NSC-32428, NSC759150, Taurine-Supplied by Selleck Chemicals, AKOS005208848, Tox21_110277_1, CCG-205208, CS-2397, DB01956, Ethanesulfonic acid, 2-amino- (9CI), LP01134, MCULE-6041857208, NE10562, NSC-759150, RP17828, RTR-001805, TRA-0183757, NCGC00015997-01, NCGC00015997-02, NCGC00015997-03, NCGC00015997-04, NCGC00015997-05, NCGC00015997-07, NCGC00015997-08, NCGC00015997-10, NCGC00024497-01, NCGC00024497-02, NCGC00024497-03, NCGC00024497-04, NCGC00024497-05, NCGC00260069-01, NCGC00261819-01, AJ-45668, AK106168, AN-22475, BT000122, I815, NCI60_002814, OR199254, AB1002120, KB-259903, ST2409585, TL8000260, TR-001805, A0295, AM20080018, EU-0101134, FT-0611241, C00245, D00047, T 0625, AB00443712-07, I09-0069

Removed Synonyms

Taurine Hydrochloride, Taurine, Monopotassium Salt, Taurine Zinc Salt (2:1), CID1123, Piperazine-N,N’-bis(2-ethanesulfonic acid), 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, D013654, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, EPE, MES, PIN

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