Preparation of diacetonamine
50 ml of mesityl oxide are dissolved in 100 ml of alcohol, cooled in a freezing mixture to -10° C, and dry ammonia is passed into the solution until saturated. The solution is allowed to stand for 48 hours. The diacetonamine base is separated as the acid oxalate. 30 g of powdered oxalic acid are mixed with 120 ml of alcohol in a beaker placed in ice. The ammoniacal solution is gradually added with vigorous stirring so that the temperature does not rise above 20° C until the pasty mass is neutral. To the resulting mixture, which is nearly solid, further 30 g of powdered oxalic acid are added and stirred. The reaction mixture is poured in a round bottom flask fitted with reflux condenser and boil for 15 minutes to complete the reaction. The diacetonamine hydrogenoxalate is filtered hot and the solution cooled slowly to 0° C. The diacetonamine hydrogenoxalate separates in crusts, which are filtered. The yield from 50 ml of mesityl oxide is about 50 g of diacetonamine hydrogenoxalate. Diacetonamine can also be prepared directly by the action of ammonia on acetone.
A Class-Book of Organic Chemistry, by J. B. Cohen, 12, 1919
Diacetonamine, 2-Pentanone, 4-amino-4-methyl-, 4-Amino-4-methylpentan-2-one, 4-Amino-4-methyl-2-pentanone, UNII-WI13YZU3HT, WI13YZU3HT, AC1L2BP2, AC1Q5CG5, SCHEMBL690783, AC1Q1K45, CQTRUFMMCCOKTA-UHFFFAOYSA-N, MolPort-001-779-724, EINECS 210-876-8, AR-1I3735, AKOS006220717, 4CN-0963, 4-Amino-4-Methyl-2-Pentanone Hydrogen Oxalate, L-1557, 4-AMINO-4-METHYL-2-PENTANONEHYDROGENOXALATE, S14-1063, 3B3-049810
CID69361, 625-04-7, 6342-21-8