Synthesis of 1,3-propane sultone

Preparation of 1,3-propane sultone

Preparation of 1,3-propane sultone

Preparation of 1,3-propane sultone

3-hydroxy-1-propanesulfonic acid and water were added into a round bottom flask in an oil bath, then 3-hydroxy-1-propanesulfonic acid performed vacuum distillation and intermolecular dehydration to synthesize 1,3-propane sultone in the stirring condition; the product 1,3-propane sultone of 205-230° C was collected, the yield was 95%. Density: 1.39 g/cm³; Boiling point: 112 °C; Melting point: 31 °C.

Journal of Chemical Science and Technology,  Vol. 2 Iss. 4, 209-212, 2013.


oxathiolane 2,2-dioxide



InChI Key


Canonical SMILES


MeSH Synonyms

1,3-propane sultone, propane sultone

Depositor-Supplied Synonyms

1,3-Propanesultone, Propane sultone, 1120-71-4, 1,3-PROPANE SULTONE, 1,2-oxathiolane 2,2-dioxide, Propanesultone, 1,2-Oxathiolane, 2,2-dioxide, .gamma.-Propane sultone, oxathiolane 2,2-dioxide, RCRA waste number U193, NSC 42386, 3-Hydroxy-1-propanesulfonic acid gamma-sultone, RCRA waste no. U193, CCRIS 535, 3-Hydroxy-1-propanesulphonic acid sultone, 1,2-Oxathrolane 2,2-dioxide, 3-Hydroxythietane-1,1-Dioxide, CHEBI:82370, HSDB 1673, FSSPGSAQUIYDCN-UHFFFAOYSA-N, EINECS 214-317-9, BRN 0109782, 3-Hydroxy-1-propanesulfonic acid, sultone, 3-Hydroxypropanesulfonic acid gamma-sultone, AI3-26990, 3-HYDROXYPROPANESULFONIC ACID SULTONE, ST51038136, DSSTox_CID_1195, DSSTox_RID_76004, DSSTox_GSID_21195, 1-Propanesulfonic acid, 3-hydroxy-, gamma-sultone, CAS-1120-71-4, SULTONE, propane-1,3-sultone, PROPYL SULTONE, WLN: T5OSWTJ, UNII-L6NTK7VJX9, L6NTK7VJX9, 1,3-PROPANSULTONE, AC1L23GN, SCHEMBL46068, P50706_ALDRICH, 1,2-oxathiolane-2,2-dione, 2,2-dioxide-1,2-oxathiolane, 291250_ALDRICH, CHEMBL3185243, [1,2]oxathiolane 2,2-dioxide, 81815_FLUKA, 1,3-TRIMETHYLENE SULTONE, 1,2|E?-oxathiolane-2,2-dione, MolPort-003-849-987, NSC42386, ZINC4521808, Tox21_201419, Tox21_300066, UKRORGSYN-BB BBR-006774, CP0025, NSC-42386, ZINC04521808, AKOS000119611, 2,2-DIOXIDE 1,2-OXATHIOLANE, AS01254, LS-7674, LS40762, MCULE-4897687828, RL00483, RP19466, 1-Propanesulfonic acid, .gamma.-sultone, NCGC00247894-01, NCGC00247894-02, NCGC00254117-01, NCGC00258970-01, AJ-51458, AK-54023, AN-20596, BC201347, BP-21435, HE000391, HE267436, KB-10464, N099, SC-17901, TL8000352, 3-HYDROXY-1-PROPANE SULFONIC SULTONE, FT-0606745, P0324, ST24036732, 3-Hydroxy-1-propanesulfonic acid beta-sultone, B-6454, C19296, H-7365, 3-HYDROXY-1-PROPANESULFONIC ACID SULTONE, 1-Propanesulfonic acid, 3-hydroxy-.gamma.-sultone, 3-Hydroxy-1-propanesulfonic acid .gamma.-sultone, 5-19-01-00005 (Beilstein Handbook Reference), A802481, I09-0258, 1-Propanesulfonic acid, 3-hydroxy-, .gamma.-sultone, 3B3-005304, 1,2-OXATHIOLANE 2,2-DIOXIDE (1,3-PROPANE SULTONE)

Removed Synonyms

1, 2,2-dioxide, CID14264, C003218

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