Synthesis of 1-phenyl-1,2-propanedione

Preparation of 1-phenyl-1,2-propanedione

2N-Sulfuric acid (50 ml) containing mercury(II) sulfate (0.25 g) is added to a solution of benzoylacetylene (6.5 g) in ethanol (100 ml). The mixture is stirred on a boiling water-bath for 6 hours during which further mercury sulfate (0.25 g) in 2N-sulfuric acid is gradually added. Isolation by means of ether gives 1-phenyl-1,2-propanedione (4.1 g) as a yellow oil, b.p. 88°/17 mm, nD 1.5350 at 17°.

J. Chem. Soc, 1946, 945





InChI Key


Canonical SMILES


MeSH Synonyms

1-phenyl-1,2-propanedione, pyruvophenone

Depositor-Supplied Synonyms

1-PHENYL-1,2-PROPANEDIONE, 1-Phenylpropane-1,2-dione, 579-07-7, Acetylbenzoyl, Acetyl benzoyl, Benzoylacetyl, Pyruvophenone, Methylphenylglyoxal, 1,2-Propanedione, 1-phenyl-, Phenylmethyldiketone, Benzoyl methyl ketone, Methyl phenyl diketone, 3-Phenyl-2,3-propanedione, Methyl phenyl glyoxal, Phenyl methyl diketone, 1-Phenyl-propane-1,2-dione, 1-phenyl-1,2-propandione, FEMA No. 3226, CCRIS 6297, CHEBI:63552, BVQVLAIMHVDZEL-UHFFFAOYSA-N, NSC 7643, EINECS 209-435-2, MFCD00008755, SBB064017, AI3-23868, alpha-keto-propiophenone, ACMC-1ATOH, UNII-ZB5XA3GD0I, Phenyl-1,2-Propanedione, ZB5XA3GD0I, 1-phenyl-1,2-dioxopropane, 1-phenyl-1,2-propane dione, KSC494S9L, SCHEMBL180411, W322601_ALDRICH, 223034_ALDRICH, AC1L1X71, CHEMBL192258, SCHEMBL8670415, DTXSID3060372, BDBM22724, CTK3J4995, NSC7643, NSC-7643, ZINC1683675, ANW-32826, DNC005431, ZINC01683675, AKOS003382258, MCULE-5571144917, NE10607, AJ-29774, AK116651, AN-21476, CJ-06351, CJ-27768, KB-13080, OR011085, OR108656, SC-81678, AB1006062, DB-003204, LS-179806, ST2415466, 4CH-014605, AM20040761, FT-0608215, P0210, ST45024211, C17268, A831668, W-105429, InChI=1/C9H8O2/c1-7(10)9(11)8-5-3-2-4-6-8/h2-6H,1H, 30581-69-2

Removed Synonyms

1, 1-phenyl-, C9H8O2, MolPort-001-780-114, CID11363, RT-002303, C100349

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