Synthesis of ethyl bromide

Preparation of ethyl bromide

Preparation of ethyl bromide from ethanol and hydrobromic acid

Preparation of ethyl bromide from ethanol and hydrobromic acid

Preparation of ethyl bromide from ethanol and hydrobromic acid

A 1-liter two-necked round bottomed flask is fitted with a dropping funnel and a wide bent tube connected to a long efficient condenser set for downward distillation and a receiver. 281 ml (or 415 grams) of 48% hydrobromic acid are placed in the flask and 65 ml (or 120 grams) of concentrated sulfuric acid are added in portions, with shaking. When cold, 145 ml (or 100 grams) of 95% ethyl alcohol are slowly added in small portion to the mixture of sulfuric and hydrobromic acids. 109 ml (or 200 g) of concentrated sulfuric acid are slowly added from the dropping funnel and the obtained ethyl bromide is slowly distilled  and collected in an ice cooled receiving flask. The crude ethyl bromide is washed with an equal volume of concentrated hydrochloric acid, then with water, a little 5% sodium bicarbonate solution, with water and finally ethyl bromide is dried with anhydrous calcium chloride. The crude ethyl bromide is purified by distillation. The fraction passing over 38-39° C is collected in a receiver cooled in ice, yielding 205 grams of pure ethyl bromide.

A text book of practical organic chemistry, by A. I. Vogel, 278-279, 1974

Preparation of ethyl bromide from ethanol and potassium bromide

Preparation of ethyl bromide from ethanol and potassium bromide

Preparation of ethyl bromide from ethanol and potassium bromide

25 g of ethyl alcohol are added to 50 g of concentrated sulfuric acid with continual stirring. The mixture is allowed to cool and is poured on to 60 g of finely powdered potassium bromide. The reaction mixture is allowed to stand over-night. The next day ethyl bromide is distilled over and washed, first with dilute sodium carbonate solution and then several times with water. The obtained ethyl bromide is dried with calcium chloride and redistilled.

Preparation of organic compounds, E. de. Barry Barnett, 68-69, 1912

Preparation of ethyl bromide from ethanol and bromine

Preparation of ethyl bromide from ethanol and bromine

Preparation of ethyl bromide from ethanol and bromine

To the round bottom flask which is cooled with ice-cold water, a mixture of 60 g of ethyl alcohol and 10 g of red phosphorus are placed. From a dropping funnel slowly 60 g of bromine are added while the reaction mixture is stirred and well cooled. When all the bromine has been added the mixture is stirred additionally for 1 hour. Then ethyl bromide is distilled over and washed, first with dilute sodium carbonate solution and then several times with distilled water. Finally, ethyl bromide is dried with calcium chloride and redistilled yielding colorless heavy liquid boiling at 38° C.

Preparation of organic compounds, E. de. Barry Barnett, 68-69, 1912

IUPAC Name

bromoethane

InChI

InChI=1S/C2H5Br/c1-2-3/h2H2,1H3

InChI Key

RDHPKYGYEGBMSE-UHFFFAOYSA-N

Canonical SMILES

CCBr

MeSH Synonyms

bromoethane

Depositor-Supplied Synonyms

Bromoethane, ETHYL BROMIDE, Ethane, bromo-, 1-Bromoethane, 74-96-4, Monobromoethane, Bromic ether, Bromure d’ethyle, Hydrobromic ether, ethylbromide, Bromo-ethane, Etylu bromek, Halon 2001, NCI-C55481, Bromoethane (ethyl bromide), Etylu bromek [Polish], NSC 8824, CCRIS 2504, HSDB 532, RDHPKYGYEGBMSE-UHFFFAOYSA-N, EINECS 200-825-8, SBB040912, UN1891, NCI-554813, AI3-04462, BBX, Bromodiborane, Ethylbromidium, bromo ethane, 1-bromo ethane, ACMC-1BHYF, 1-BROMO-ETHANE, C2H5Br, AC1L1MAL, DSSTox_CID_199, AC1Q27CU, AC1Q2RL2, SCHEMBL2322, DSSTox_RID_75428, UNII-LI8384T9PH, DSSTox_GSID_20199, WLN: E2, KSC377G1B, CHEMBL156378, LI8384T9PH, SCHEMBL2319234, 03150_FLUKA, CTK2H7310, NSC8824, MolPort-000-872-074, 124052_SIAL, 239607_SIAL, NSC-8824, Tox21_200355, ANW-36549, AR-1I0797, Ethyl bromide [UN1891] [Poison], AKOS000118754, Ethyl bromide [UN1891] [Poison], LS-1635, MCULE-9840669634, RP18912, RTR-031646, UN 1891, CAS-74-96-4, NCGC00091117-01, NCGC00091117-02, NCGC00257909-01, AN-41973, KB-48469, S813, InChI=1/C2H5Br/c1-2-3/h2H2,1H, TL8000307, TR-031646, B0588, FT-0614786, FT-0623246, ST50214515, C19354, 21298-EP2314295A1, 45281-EP2298746A1, 45281-EP2298756A1, 45281-EP2311806A2, 45281-EP2371831A1, 45378-EP2272822A1, 45378-EP2280012A2, 45378-EP2287165A2, 45378-EP2287166A2, 45378-EP2292620A2, 45378-EP2311806A2, 45378-EP2311824A1, 3B4-0651, I14-5818

Removed Synonyms

CID6332, C037311, 109-70-6, 78718-52-2

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