Preparation of dimephosphon
To a mixture of 110 gr dimethylphospite (1 mol) and 110 gr of mesityle oxide was slowly added 30% solution of 0.3 mol sodium methylate in methanol at room temperature while cooling. After this mixture was mixed overnight and methanol was distilled off. The obtained residue was distilled in vacuum. The fraction boiling at 135-140 C/20 mm was collected and in order to obtain pure dimephosphon re-distilled one more time. Yield 124 gr (61%). Purity 98%. Light yellow liquid.
Synthesis submitted and performed by Rinat Miftakhov.
(1,1-dimethyl-3-oxobutyl)phosphonic acid dimethyl ester, dimephosphon
dimephosphon, (1,1-Dimethyl-3-oxobutyl)phosphonic acid dimethyl ester, dimethyl(2-methyl-4-oxopentan-2-yl)phosphonate, Phosphonic acid, (1,1-dimethyl-3-oxobutyl)-, dimethyl ester, 14394-26-4, Mitsefosfon, AC1Q6SDO, AC1L3U4S, UNII-136CQC28US, 136CQC28US, SCHEMBL8350477, CTK3E9195, ZINC5159502, AR-1I5740, OR221075, 4-dimethoxyphosphoryl-4-methylpentan-2-one, LS-106582
C8H17O4P, CID122179, 86003-41-0, 92431-51-1