Synthesis of 2-chloro-4-(hydroxymethyl)phenol

Preparation of 2-chloro-4-(hydroxymethyl)phenol

Preparation of 2-chloro-4-(hydroxymethyl)phenol

Preparation of 2-chloro-4-(hydroxymethyl)phenol

2-Chloro-4-(hydroxymethyl)phenol is obtained by boiling 2-chloro-4-(chloromethyl)phenol with water. After cooling, it is extracted with ether, and the ether removed by distillation. A clear yellow oil remains which becomes crystalline when the sides of the vessel are scratched. It is recrystallised from benzene, and forms colourless needles which melt at 123° C.

Preparation of organic compounds, E. de. Barry Barnett, 100, 1912

IUPAC Name

2-chloro-4-(hydroxymethyl)phenol

InChI

InChI=1S/C7H7ClO2/c8-6-3-5(4-9)1-2-7(6)10/h1-3,9-10H,4H2

InChI Key

KWFBSEGXKSQRCG-UHFFFAOYSA-N

Canonical SMILES

C1=CC(=C(C=C1CO)Cl)O

Depositor-Supplied Synonyms

2-chloro-4-(hydroxymethyl)phenol, 105960-29-0, NSC85481, AC1L5WT8, NCIOpen2_001258, SCHEMBL507053, 2-Chloro-4-hydroxymethylphenol, 2-Chloro-4-hydroxymethyl-phenol, 3-Chloro-4-hydroxybenzyl alchol, CTK8A2779, 3-Chloro-4-hydroxybenzyl alcohol, KWFBSEGXKSQRCG-UHFFFAOYSA-N, MolPort-014-166-507, ZINC1760433, NSC-85481, AKOS010948091, MCULE-6186539873, NE61730, OR041602, OR189686, SC-62217, BENZENEMETHANOL,3-CHLORO-4-HYDROXY, KB-283772, I14-40818

Removed Synonyms

CID257456

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