Synthesis of 2,2-difluorooctane

Preparation of 2,2-difluorooctane

Preparation of 2,2-difluorooctane

Preparation of 2,2-difluorooctane

100 g of anhydrous HF in 74 g of ether or 56 g of acetone are introduced through a copper tube into an ice-cooled 500-ml copper flask, then 1 mole of 1-octyne is dropped in as slowly as possible. The mixture is allowed to warm to room temperature and after 1 hour is poured on ice. The organic layer is separated and distilled (b.p. 137.5° C). The yield of 2,2-difluorooctane is 70-90%.

J. Amer. Chem. Soc, 65, 587 (1943).

IUPAC Name

2,2-difluorooctane

InChI

InChI=1S/C8H16F2/c1-3-4-5-6-7-8(2,9)10/h3-7H2,1-2H3

InChI Key

NKILRFSBLPCELT-UHFFFAOYSA-N

Canonical SMILES

CCCCCCC(C)(F)F

Depositor-Supplied Synonyms

SCHEMBL11545308

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