Synthesis of 2,2-dichloropropane (propane, 2,2-dichloro-; dimethyldichloromethane)

Preparation of 2,2-dichloropropane

Preparation of 2,2-dichloropropane (propane, 2,2-dichloro-; dimethyldichloromethane)

Preparation of 2,2-dichloropropane (propane, 2,2-dichloro-; dimethyldichloromethane)

15 g of phosphorus pentachloride is a slowly added in small portion to 5 g of well cooled with ice water acetone. The phosphorus pentachloride reacts with acetone and dissolves, forming yellow color liquid. When all phosphorus pentachloride is added and dissolved the reaction solution is poured into ice-cold water. The obtained solution is kept until the phosphorus oxychloride decomposes by dissolving in water. 2,2-Dichloropropane forms as the heavy liquid, which settles to the bottom of the flask with chloroform-like odor. 2,2-Dichloropropane is separated by means of separatory funnel, well washed with water, then diluted solution of sodium carbonate and again with water in order to remove inorganic acid. After drying over anhydrous calcium chloride, crude 2,2-dichloropropane is purified by distillation, collecting fraction boiling at 70° C.

A class-book of organic chemistry, by J. B. Cohen, 67, 1918





InChI Key


Canonical SMILES


MeSH Synonyms


Depositor-Supplied Synonyms

2,2-DICHLOROPROPANE, Propane, 2,2-dichloro-, Dimethyldichloromethane, 594-20-7, Dichlorodimethylmethane, R 270aa, CCRIS 9221, EINECS 209-832-0, Isopropylidene dichloride, DSSTox_CID_10060, DSSTox_RID_78836, DSSTox_GSID_30060, CAS-594-20-7, Acetone Dichloride, Isopropylidene Chloride, 2,2-Dichloro-propane, AC1L1XUC, ACMC-1AM00, UNII-C5V432N6XB, SCHEMBL90709, 47752U_SUPELCO, 258571_ALDRICH, C5V432N6XB, CHEMBL349587, CTK1H0772, MolPort-001-789-599, ZEOVXNVKXIPWMS-UHFFFAOYSA-N, Tox21_202311, Tox21_303540, ANW-33258, LS-2160, NCGC00091723-01, NCGC00091723-02, NCGC00257301-01, NCGC00259860-01, AN-21561, CJ-32109, KB-86281, TC-122003, D0400, FT-0609218, S0624, InChI=1/C3H6Cl2/c1-3(2,4)5/h1-2H, 3B4-2663, I14-85764, UNII-B8X7551QF3 component ZEOVXNVKXIPWMS-UHFFFAOYSA-N

Share This

Leave a Reply

Your email address will not be published. Required fields are marked *