Synthesis of 1-bromo-3-chloropropane (trimethylene chlorobromide)

Preparation of 1-bromo-3-chloropropane

1-bromo-3-chloropropane is prepared by reacting allyl chloride with hydrobromic acid:

Preparation of 1-bromo-3-chloropropane (trimethylene chlorobromide)

Preparation of 1-bromo-3-chloropropane (trimethylene chlorobromide)

The 1 mole of allyl chloride was heated in pressure reaction vessel for seven or eight hours with 2 moles of hydrobromic acid (d=1.65) which contains 70% of hydrogen bromide. The hydrobromic acid of this strength was made by passing gaseous hydrogen bromide gas evolved from sodium bromide and sulfuric acid, into water and saturating it at 12-15° C. When the reaction was complete the content was distilled by collecting fraction passing at around 144-145 °C.

The synthesis of amino acids, by B. B. Wilcox, 23, 1904

IUPAC Name

1-bromo-3-chloropropane

InChI

InChI=1S/C3H6BrCl/c4-2-1-3-5/h1-3H2

InChI Key

MFESCIUQSIBMSM-UHFFFAOYSA-N

Canonical SMILES

C(CCl)CBr

MeSH Synonyms

1-bromo-3-chloropropane

Depositor-Supplied Synonyms

1-BROMO-3-CHLOROPROPANE, 109-70-6, 3-Bromopropyl chloride, 1-Chloro-3-bromopropane, 3-Chloro-1-bromopropane, Trimethylene chlorobromide, Propane, 1-bromo-3-chloro-, 3-Chloropropyl bromide, 3-Bromo-1-chloropropane, Trimethylene bromide chloride, 1,3-Chbp, .omega.-Chlorobromopropane, 1,3-Chlorbromopropane, omega-Chlorobromopropane, I-BCP, l-Chloro-3-bromopropane, NSC 9183, Trimethylene bromochloride, 1-Bromo-3-chloro-propane, CCRIS 6536, HSDB 5394, MFESCIUQSIBMSM-UHFFFAOYSA-N, EINECS 203-697-1, SBB058669, UN2688, BRN 0605278, bromopropylchloride, 3-bromochloropropane, 3-chlorobromopropane, 3-chloropropylbromide, 3-chloro-bromopropane, 1-bromo-3chloropropane, 1bromo-3-chloropropane, 3-chloro1-bromopropane, 3chloro-1-bromopropane, ACMC-1BUXC, 1,3-aaAE+/-uIe, 1 -bromo-3-chloropropane, 1-bromo-3- chloropropane, 1-bromo-3-chloro propane, 1-chloro-3-bromo-propane, 3-bromo-1-chloro propane, 3-bromo-1-chloro-propane, 3-chloro-1- bromopropane, UNII-KA4WR2LS00, 3-chloro-1-propyl bromide, AC1L1Q1R, SCHEMBL9330, KA4WR2LS00, B62404_ALDRICH, KSC174M2P, B9673_SIGMA, 1-bromanyl-3-chloranyl-propane, CHEMBL156560, CTK0H4627, NSC9183, MolPort-001-783-421, PROPANE,1-BROMO,3-CHLORO, NSC-9183, AN-983, ANW-16084, AKOS000121201, EyNC(1/4)x>>uAEaa>> masculineIIi, MCULE-7937580875, RP22132, RTR-002080, UN 2688, AK105872, I843, SC-19098, KB-152371, LS-119641, TR-002080, B0575, FT-0607482, FT-0615245, FT-0615246, ST24037874, ST51037167, 1-Bromo-3-chloropropane [UN2688] [Poison], InChI=1/C3H6BrCl/c4-2-1-3-5/h1-3H, 1-Bromo-3-chloropropane [UN2688] [Poison], 20664-EP2284169A1, 20664-EP2287161A1, 20664-EP2287162A1, 20664-EP2292615A1, 20664-EP2308833A2, 20664-EP2311824A1, 20664-EP2314585A1, 20664-EP2371808A1, 51205-EP2311824A1, 4-01-00-00212 (Beilstein Handbook Reference), A802077, 3B4-1028, I14-0241

Removed Synonyms

CID8006

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