Synthesis of 1,3-dibromoacetone

Preparation of 1,3-dibromoacetone

Preparation of 1,3-dibromoacetone

Preparation of 1,3-dibromoacetone

650 ml bromine (1.8 moles per 1 mole of acetone) are slowly added dropwise to a mixture containing 500 ml of acetone, 1600 ml of water, and 375 ml of glacial acetic acid at 70°. After the reaction is complete fraction distillation yields 20 g 1,1-dibromoacetone, 473 g of 1,3-dibromoacetone (b.p. 97-98°/21-22 mm), and 60 g of monobromoacetone (b.p. 137 °C).

Preparative Organic Chemistry, by Weygand/Hilgetag, 187, (1972).





InChI Key


Canonical SMILES


MeSH Synonyms

1,3-dibromo-2-propanone, 1,3-dibromopropanone

Depositor-Supplied Synonyms

1,3-Dibromoacetone, 816-39-7, 1,3-dibromopropan-2-one, 1,3-Dibromo-2-propanone, 1,3-dibromopropanone, 2-Propanone, 1,3-dibromo-, LQQKDSXCDXHLLF-UHFFFAOYSA-N, sGQDLLRxbRwSP@, ACMC-20ap4e, 2-Propanone,3-dibromo-, 1,3-dibromo-2-propanon, C3H4Br2O, AC1L2D1B, 1,3-Dibromo-propan-2-one, KSC449S3P, SCHEMBL228965, AC1Q27G7, AMOT0225, 1,3-Dibromopropan-2-one, tech, CTK3E9937, MolPort-002-498-936, KST-1B8933, ZINC1767938, EINECS 212-430-8, AR-1B6818, CD0221, GEO-00967, NSC249810, ZINC01767938, 1,3-DIBROMO ACETONE (SYM.), AKOS005206860, AM85919, NSC 249810, NSC-249810, OR16995, RTR-025645, TRA0008001, AK150791, OR023998, DB-056547, KB-216429, TR-025645, FT-0606625, FT-0666475, X3125, A20840, 3B3-049977

Removed Synonyms

Lithium diethylamide, DIBROMOACETONE, CID69952, 86315-69-7

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