Synthesis of (2-chloro-2-ethoxyethyl)benzene

Preparation of (2-chloro-2-ethoxyethyl)benzene

Preparation of (2-chloro-2-ethoxyethyl)benzene

Preparation of (2-chloro-2-ethoxyethyl)benzene

Dry hydrogen chloride (11.5 g) is passed rapidly, with stirring, into an ice-cold mixture of phenylacetaldehyde (32.5 g), ethanol (12.5 g), and anhydrous sodium sulfate (30 g). The liquid product is decanted, calcium chloride (16g) is added and the mixture is kept at 20 mm for 45min for removal of hydrochloric acid. The yield of crude product is 94%.

J. Amer. Chem. Soc, 71, 4007 (1949).

 

IUPAC Name

(2-chloro-2-ethoxyethyl)benzene

InChI

InChI=1S/C10H13ClO/c1-2-12-10(11)8-9-6-4-3-5-7-9/h3-7,10H,2,8H2,1H3

InChI Key

FDAJAWNRAQDVDA-UHFFFAOYSA-N

Canonical SMILES

CCOC(CC1=CC=CC=C1)Cl

Depositor-Supplied Synonyms

SCHEMBL14667805, (2-chloro-2-ethoxyethyl)benzene, (2-chloro-2-ethoxy-ethyl)-benzene

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