Synthesis of (2-chloro-1,1,2-trifluoroethyl)diethylamine

Preparation of (2-chloro-1,1,2-trifluoroethyl)diethylamine

Preparation of (2-chloro-1,1,2-trifluoroethyl)diethylamine

Preparation of (2-chloro-1,1,2-trifluoroethyl)diethylamine

40 g (0.56 mol) of diethylamine are placed in a Drechsel bottle and cooled to —5° to —10 °C. Then 70 g (0.6 mol) of thoroughly dried chlorotrifluoroethylene is bubbled through it during 10 hours. The reaction product is distilled in vacuum yield 70 g (66 %) of (2-chloro-1,1,2-trifluoroethyl)diethylamine; bp 32°-33 °C/6 mm Hg.

Zh. Obshch. Khim. 29, 2159 (1959)

IUPAC Name

2-chloro-N,N-diethyl-1,1,2-trifluoroethanamine

InChI

InChI=1S/C6H11ClF3N/c1-3-11(4-2)6(9,10)5(7)8/h5H,3-4H2,1-2H3

InChI Key

BDZHKUAKSMWSAJ-UHFFFAOYSA-N

Canonical SMILES

CCN(CC)C(C(F)Cl)(F)F

Depositor-Supplied Synonyms

(2-Chloro-1,1,2-trifluoroethyl)diethylamine, 357-83-5, N,N-Diethyl(2-chloro-1,1,2-trifluoroethyl)amine, Ethanamine, 2-chloro-N,N-diethyltrifluoro-, ST51040170, 2-chloro-n,n-diethyl-1,1,2-trifluoroethanamine, Yarovenko’s reagent, ACMC-20appo, AC1L37XO, AC1Q4KK6, SCHEMBL966410, CTK0C7283, BDZHKUAKSMWSAJ-UHFFFAOYSA-N, MolPort-001-775-824, AR-1E0648, SBB091007, AKOS007930480, MCULE-4817689134, OR013141, OR136407, OR205113, 2-chloro-1,1,2-trifluoroethyldiethylamine, TC-172995, FT-0691641, 1-diethylamino-1,1,2trifluoro-2-chloroethane, 1-diethylamino-1,1,2-trifluoro-2-chloroethane, 2-chloro-1-diethylamino-1,1,2-trifluoroethane, diethyl (2-chloro-1,1,2-trifluoroethyl)amine, diethyl (2-chloro-1,1,2-trifluoro-ethyl) amine, diethyl (2-chloro-1,1,2-trifluoro-ethyl)amine, diethyl (2-chloro-1,1,2trifluoro-ethyl) amine, N-(2-chloro-1,1,2-trifluoroethyl)-diethylamine, N-(2-Chloro-1,1,2-trifluoroethyl)diethylamine, 3B3-082997, I14-107182, 114440-20-9

Removed Synonyms

CID136184, 36932-41-9

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