Synthesis of 1-methoxynaphthalene

Preparation of 1-methoxynaphthalene

Preparation of 1-methoxynaphthalene

Preparation of 1-methoxynaphthalene

10 g of 1-naphthol are dissolved in 40 g of 10% sodium hydroxide solution, and the cooled liquid mixed with 8 ml of dimethyl sulphate, with continuous shaking. Gentle warming may be needed to start the reaction. The 1-methoxynaphthalene separates as a solid which is filtered off after boiling and making alkaline if necessary, with sodium hydroxide, precipitate filtered at the pump, and well washed with water. It is dissolved in ether, filtered, the ether removed on a water bath, and the residue recrystallised from dilute alcohol. Yield almost theoretical. Lustrous plates; insoluble in water; soluble in ether and in hot alcohol; m.p. 71° C.

Systematic organic chemistry, by W. M. Cumming, 128, 1937.

IUPAC Name

1-methoxynaphthalene

InChI

InChI=1S/C11H10O/c1-12-11-8-4-6-9-5-2-3-7-10(9)11/h2-8H,1H3

InChI Key

NQMUGNMMFTYOHK-UHFFFAOYSA-N

Canonical SMILES

COC1=CC=CC2=CC=CC=C21

MeSH Synonyms

1-methoxynaphthalene

Depositor-Supplied Synonyms

1-METHOXYNAPHTHALENE, 2216-69-5, Naphthalene, 1-methoxy-, Methyl 1-naphthyl ether, 1-methoxy naphthalene, .alpha.-Methoxynaphthalene, Methoxynaphthalene, alpha-Methoxynaphthalene, alpha-Naphthyl methyl ether, .alpha.-Naphthyl methyl ether, NQMUGNMMFTYOHK-UHFFFAOYSA-N, NSC 5530, EINECS 218-696-1, SBB057507, AI3-02144, 1-Methoxynapthalene, 1-methoxy-naphthalene, ACMC-1AZDL, 1-Naphthol methyl ether, 1-Naphthyl methyl ether, UNII-DG2EOL57LF, DG2EOL57LF, AC1L28FX, KSC203A2L, SCHEMBL151449, 154571_ALDRICH, SCHEMBL3504381, SCHEMBL10251245, CTK1A3025, NSC5530, MolPort-003-926-806, NSC-5530, ZINC1686999, ANW-24758, ZINC01686999, AKOS003632549, MCULE-9145939167, RL02686, RTC-040329, TRA0057714, TRA0065622, AC-18227, AJ-29874, AK105904, AN-50560, CJ-27880, KB-12712, LS-94757, OR001671, DB-019236, ST2408800, TC-040329, FT-0608014, M0116, ST50824687, M-9168, A815983, I14-1584, Q-200124, 3B3-012820, InChI=1/C11H10O/c1-12-11-8-4-6-9-5-2-3-7-10(9)11/h2-8H,1H, 57982-68-0

Removed Synonyms

CID16668, 1-methoxy-5,6,7,8-tetrahydronaphthalene, 21050-13-5, 21050-95-3

Share This

Leave a Reply

Your email address will not be published. Required fields are marked *