Synthesis of 1-bromo-3-nitrobenzene

Preparation of 1-bromo-3-nitrobenzene

Preparation of 1-bromo-3-nitrobenzene

Preparation of 1-bromo-3-nitrobenzene

Silver sulfate (0.1 mole) is added to nitrobenzene (0.1 mole) and bromine (0.1 mole) in concentrated sulfuric acid (90 ml) and water (10 ml), and the obtained reaction mixture is shaken at room temperature for 16 hours. Filtration from silver bromide, dilution with water, and extraction with ether give the 1-bromo-3-nitrobenzene, m.p. 55-56°, in 70% yield.

J. Chem. Soc, 1950, 573.

J. Chem. Soc, 1950,  3694.

Direct bromination of nitrobenzene by bromine and iron powder is described in detail in Org. Syn., 8, 46 (1928).

IUPAC Name

1-bromo-3-nitrobenzene

InChI

InChI=1S/C6H4BrNO2/c7-5-2-1-3-6(4-5)8(9)10/h1-4H

InChI Key

FWIROFMBWVMWLB-UHFFFAOYSA-N

Canonical SMILES

C1=CC(=CC(=C1)Br)[N+](=O)[O-]

MeSH Synonyms

3-bromonitrobenzene, o-bromonitrobenzene

Depositor-Supplied Synonyms

1-Bromo-3-nitrobenzene, 3-Bromonitrobenzene, 585-79-5, M-BROMONITROBENZENE, 3-Nitrobromobenzene, Benzene, 1-bromo-3-nitro-, m-Nitrobromobenzene, 1-bromo-3-nitro-benzene, 3-bromo-1-nitrobenzene, NSC 7084, BROMONITROBENZENE-3, CCRIS 3114, FWIROFMBWVMWLB-UHFFFAOYSA-N, EINECS 209-563-9, MFCD00024298, SBB063141, AI3-09054, ST50406626, 1-Bromo-3-nitrobenzene (unstable at 56 C) [Forbidden], 61878-56-6, 3-bromo-nitrobenzene, Benzene, bromonitro-, PubChem3820, 3-nitro-1-bromobenzene, 1-Bromo 3-nitrobenzene, 1-Nitro-3-bromobenzene, 4-Bromo-2-nitrobenzene, AC1Q5AFD, 1-bromo-3-nitro benzene, ACMC-1BN8D, AC1L1XE7, SCHEMBL85551, ghl.PD_Mitscher_leg0.921, KSC354K7R, PARAGOS 530459, DTXSID3060409, 17700_FLUKA, CTK2F4578, NSC7084, OTAVA-BB 1362062, AKOS 92443, NSC-7084, STR07175, ZINC1566594, m-Nitrobromobenzene, liquid or solid, AC-183, AN-729, ANW-32986, STK286023, ZINC01566594, AKOS000121518, AS03440, CS20650, MCULE-4598852910, PS-5118, RP25898, RP25899, TRA0043541, AJ-27145, AK-54798, BC002619, BC228014, BR-54798, CJ-05384, CJ-24628, FS003020, KB-11707, LS-29209, OR004114, OR101846, AB1009337, DB-022387, ST2408716, TC-062816, TL8003747, 1-Bromo-3-nitrobenzene (unstable at 56 C), AM20050065, B0623, A24686, B-8220, AB01333606-02, I01-0562, W-105381, InChI=1/C6H4BrNO2/c7-5-2-1-3-6(4-5)8(9)10/h1-4, m-Nitrobromobenzene, liquid or solid [UN2732] [Keep away from food], m-Nitrobromobenzene, liquid or solid [UN2732] [Keep away from food], m-Nitrobromobenzene;1-bromo-3-nitro-benzen;1-Nitro-3-brombenzen;1-Nitro-3-bromobenzene;3-Bromo-1-nitrobenzene

Removed Synonyms

null, C6H4BrNO2, UN 2732 (Related), UN2732, MolPort-000-150-460, CID11457, RTC-062816

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